Also, Li et al. have unveiled the upregulation of PI3K/AKT pathway promotes the expressions of placental growth element (PlGF) and C-X-C Motif Chemokine Ligand 1 (CXCL1) in lung most cancers stem cells, which even more promote angiogenesis [59]. CCPlenty of paracrine components secreted by MSCs are ligands for receptors that activate PI3K/AKT pathw
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